HyunGyo Pyo

Hyeon-Gyu received his B.S. in Biological Sciences from KAIST. During his undergraduate studies, he explored cellular reprogramming and brain regeneration, utilizing the spiny mouse model to investigate how the ECM composition and microenvironment regulate neural plasticity.
His fascination with how cells reset their identity naturally expanded into an interest in the epigenetic mechanisms underlying reprogramming. Captivated by the perspective that aging acts as a “software” problem of lost epigenetic information rather than a hardware failure, he joined the Yang Lab to explore the fundamental nature of this process.
Bridging his background in ECM biology with epigenetics, he currently investigates how physical microenvironments, particularly ECM stiffness, influence the epigenetic landscape and the maintenance of cellular identity. Driven by a deep passion for fundamental biological mechanisms, he aspires to mechanistically uncover the biological truths of how and why we age.